On the occasion of the 50th anniversary of the BSCDB (Belgian Society for Cell and Developmental Biology), Agnès Noël received an "Achievement Award" which recognizes the scientific impact of the work of a career.
The Metastasis Research Laboratory (O. Peulen and A. Bellahcène) provides new insight into the importance of myoferlin in pancreatic cancer. Its pharmacological targeting sensitizes PDAC cells to ferroptosis.
This study, published by Stéphanie Herkenne (Laboratory of Molecular Angiogenesis) suggests that OPA1 could be a new therapeutic target for breast cancers, especially triple-negative cancers.
Michael Herfs' team (Laboratory for Experimental Pathology, GIGA-Cancer) demonstrates that, by drastically inhibiting innate immunity, human papillomaviruses (HPV) promote the development of bacterial vaginosis.
This study from Denis Mottet's laboratory (Gene Expression and Cancer Laboratory) published in Nature Communications identifies this protein as a new target for cancer treatment.
This grant will allow her to continue his research in the field of oncology and more specifically in triple negative breast cancer (TNBC)
In an article published in Nature Communications, Francesca Rapino & Pierre Close, from the Laboratory of Cancer Signaling (GIGA), discover how the modification of transfer RNAs impacts the dynamics of protein expression.
Michael Herfs' team (Lab for Experimental Pathology, GIGA-Cancer) demonstrates the importance of blocking the oxidized form of this protein to reactivate anti-tumor immunity and improve the effectiveness of immune checkpoint inhibitors.
This grant will allow him to continue his research in order to study the role(s) of mTORC2 in mRNA translation and cellular metabolism, in the context of lung cancer development.
A collaboration between 2 GIGA teams, the Molecular Angiogenesis laboratory and the Pneumology laboratory, has identified a new role for exosomes in idiopathic pulmonary fibrosis.
